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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344785
Species: Homo sapiens
RGD Object: Gene
Symbol: PHKA2
Name: phosphorylase kinase regulatory subunit alpha 2
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PHKA2decreases expressionISOPhka2 (Mus musculus)6480464CTDLipopolysaccharides results in decreased expression of PHKA2 mRNAPMID:22185406
PHKA2multiple interactionsISOPhka2 (Mus musculus)6480464CTDDexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]; Quercetin inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PHKA2 mRNA]PMID:22185406
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