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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303075
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90ab1
Name: heat shock protein 90 alpha family class B member 1
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90ab1increases expressionISOHsp90ab1 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of HSP90AB1 mRNAPMID:15919760
Hsp90ab1multiple interactionsISOHSP90AB1 (Homo sapiens)6480464CTD[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of HSP90AB1 mRNA; [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of HSP90AB1 mRNAPMID:22777745 PMID:35877022
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