GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP2B6 | decreases activity | ISO | Cyp2b10 (Mus musculus) | 6480464 | CTD | Lithocholic Acid results in decreased activity of CYP2B10 protein | PMID:18420780 | CYP2B6 | increases expression | ISO | Cyp2b10 (Mus musculus) | 6480464 | CTD | Lithocholic Acid results in increased expression of CYP2B10 mRNA | PMID:15358766 | CYP2B6 | multiple interactions | ISO | Cyp2b10 (Mus musculus) | 6480464 | CTD | [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA; [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA; NR1I3 protein affects the reaction [Lithocholic Acid results in increased expression of CYP2B10 mRNA]; NR1I3 protein promotes the reaction [[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA]; NR1I3 protein promotes the reaction [[Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA] | PMID:15358766 PMID:19433268 PMID:20359477 | | ||||||||||||||||||||||
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