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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736560
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHX1
Name: epoxide hydrolase 1
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHX1multiple interactionsEXP 6480464CTD[Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNAPMID:17639512
EPHX1increases expressionISOEphx1 (Rattus norvegicus)6480464CTDQuercetin results in increased expression of EPHX1 mRNAPMID:18095365 PMID:21565894
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