GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ugt1a1 | increases expression | EXP | | 6480464 | CTD | Quercetin results in increased expression of UGT1A1 mRNA | PMID:21565894 | Ugt1a1 | decreases activity | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased activity of UGT1A1 protein | PMID:35063619 | Ugt1a1 | increases expression | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of UGT1A1 mRNA | PMID:12756216 PMID:29584932 | Ugt1a1 | increases glucuronidation | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | UGT1A1 protein results in increased glucuronidation of Quercetin | PMID:11442279 PMID:14557274 | Ugt1a1 | multiple interactions | ISO | UGT1A1 (Homo sapiens) | 6480464 | CTD | AHR gene mutant form inhibits the reaction [Quercetin results in increased expression of UGT1A1 mRNA]; chrysin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Quercetin] | PMID:11442279 PMID:29584932 | |
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