GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Msh2 | affects expression | ISO | MSH2 (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide affects the expression of MSH2 mRNA | PMID:26519223 | Msh2 | increases expression | ISO | MSH2 (Homo sapiens) | 6480464 | CTD | [Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein | PMID:15081873 | Msh2 | multiple interactions | ISO | MSH2 (Homo sapiens) | 6480464 | CTD | [Hydrogen Peroxide co-treated with Quinic Acid analog] results in increased expression of MSH2 mRNA; MSH2 protein inhibits the reaction [POLK protein results in decreased susceptibility to Hydrogen Peroxide]; Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]; SN50 peptide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein] | PMID:15081873 PMID:21751221 PMID:31294882 | | ||||||||||||||||||||||
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