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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352737
Species: Homo sapiens
RGD Object: Gene
Symbol: DGAT2
Name: diacylglycerol O-acyltransferase 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DGAT2increases expressionEXP 6480464CTDEthanol results in increased expression of DGAT2 mRNAPMID:24144995
DGAT2multiple interactionsEXP 6480464CTDPER1 protein promotes the reaction [Ethanol results in increased expression of DGAT2 mRNA]PMID:24144995
DGAT2affects expressionISODgat2 (Mus musculus)6480464CTDEthanol affects the expression of DGAT2 mRNAPMID:30319688
DGAT2increases expressionISODgat2 (Mus musculus)6480464CTDEthanol results in increased expression of DGAT2 mRNA; Ethanol results in increased expression of DGAT2 proteinPMID:18620774 PMID:20637825 PMID:24144995 PMID:24146112 PMID:24892905 PMID:29317476 PMID:36535314
DGAT2increases expressionISODgat2 (Rattus norvegicus)6480464CTDEthanol results in increased expression of DGAT2 mRNAPMID:24146112
DGAT2multiple interactionsISODgat2 (Mus musculus)6480464CTD[ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of DGAT2 mRNA; Chlormethiazole promotes the reaction [Ethanol results in increased expression of DGAT2 protein]; dioscin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]; PER1 gene mutant form inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]; tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]; Thymol inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]PMID:20637825 PMID:23692951 PMID:24144995 PMID:24146112 PMID:24892905 PMID:29317476 PMID:36535314
DGAT2multiple interactionsISODgat2 (Rattus norvegicus)6480464CTDdioscin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA]PMID:24146112
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