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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736485
Species: Mus musculus
RGD Object: Gene
Symbol: Sqstm1
Name: sequestosome 1
Acc ID: CHEBI:16113
Term: cholesterol
Definition: A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
Chemical ID: MESH:D002784
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sqstm1multiple interactionsEXP 6480464CTDCholesterol inhibits the reaction [Cadmium Chloride results in decreased expression of SQSTM1 protein]PMID:29486218
Sqstm1increases expressionISOSQSTM1 (Homo sapiens)6480464CTDCholesterol results in increased expression of SQSTM1 proteinPMID:28275691
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