GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2d22 | decreases activity | EXP | | 6480464 | CTD | Tretinoin results in decreased activity of CYP2D22 protein | PMID:18420780 | Cyp2d22 | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of CYP2D22 mRNA | PMID:36189433 | Cyp2d22 | multiple interactions | EXP | | 6480464 | CTD | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP2D22 mRNA | PMID:36189433 | Cyp2d22 | decreases activity | ISO | CYP2D6 (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased activity of CYP2D6 protein | PMID:18420780 | |
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