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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:113455
Term: sodium benzoate
Definition: An organic sodium salt resulting from the replacement of the proton from the carboxy group of benzoic acid by a sodium ion.
Chemical ID: MESH:D020160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityEXP 6480464CTDSodium Benzoate results in increased activity of CASP3 proteinPMID:32911041
Casp3increases expressionEXP 6480464CTDSodium Benzoate results in increased expression of CASP3 proteinPMID:35187746
Casp3multiple interactionsEXP 6480464CTDAscorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein]PMID:35187746
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDSodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein]PMID:11329530
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