GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cldn1 | affects expression | ISO | Cldn1 (Mus musculus) | 6480464 | CTD | deoxynivalenol affects the expression of CLDN1 protein | PMID:24568843 | Cldn1 | decreases expression | ISO | CLDN1 (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in decreased expression of CLDN1 protein | PMID:28865950 | Cldn1 | decreases expression | ISO | Cldn1 (Mus musculus) | 6480464 | CTD | deoxynivalenol results in decreased expression of CLDN1 mRNA; deoxynivalenol results in decreased expression of CLDN1 protein | PMID:34506767 PMID:35381244 PMID:35817260 | Cldn1 | increases expression | ISO | CLDN1 (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in increased expression of CLDN1 mRNA | PMID:24568843 | Cldn1 | multiple interactions | ISO | CLDN1 (Homo sapiens) | 6480464 | CTD | [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein; deoxynivalenol results in decreased expression of and affects the localization of CLDN1 protein | PMID:24568843 PMID:28865950 PMID:28935499 | Cldn1 | multiple interactions | ISO | Cldn1 (Mus musculus) | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] | PMID:34506767 PMID:35381244 PMID:35817260 | | ||||||||||||||||||||||
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