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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2752
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gss
Name: glutathione synthetase
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gssincreases expressionISOGSS (Homo sapiens)6480464CTDdeoxynivalenol results in increased expression of GSS mRNAPMID:37419272
Gssmultiple interactionsISOGSS (Homo sapiens)6480464CTDResveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GSS protein]; Resveratrol promotes the reaction [deoxynivalenol results in increased expression of GSS protein]PMID:37419272
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