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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737357
Species: Homo sapiens
RGD Object: Gene
Symbol: IGFBP2
Name: insulin like growth factor binding protein 2
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGFBP2decreases expressionISOIgfbp2 (Rattus norvegicus)6480464CTDTamoxifen results in decreased expression of IGFBP2 mRNAPMID:17630414
IGFBP2increases expressionISOIgfbp2 (Mus musculus)6480464CTDTamoxifen results in increased expression of IGFBP2 mRNAPMID:17555576
IGFBP2multiple interactionsISOIgfbp2 (Rattus norvegicus)6480464CTD[Tamoxifen co-treated with bexarotene] results in increased expression of IGFBP2 mRNAPMID:17630414
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