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GENE - TERM ANNOTATION REPORT

RGD ID: 736979
Species: Mus musculus
RGD Object: Gene
Symbol: Capn10
Name: calpain 10
Acc ID: DOID:9352
Term: type 2 diabetes mellitus
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Diabetes "DO" "DO", http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Capn10 IEP 7247733RGD  
Capn10 ISOCapn10 (Rattus norvegicus)737693RGDDNA:SNP 
Capn10 ISOCapn10 (Rattus norvegicus)1625063RGDmRNA:decreased expression 
Capn10 ISOCAPN10 (Homo sapiens)1625049RGDDNA:polymorphism 
Capn10 ISOCAPN10 (Homo sapiens)4107074RGDmRNA:increased expression:pancreas 
Capn10 ISOCAPN10 (Homo sapiens)7247734RGDassociated with Hypertension;DNA:SNPs:intron:rs3792267, rs2975760 (human) 
Capn10 ISOCAPN10 (Homo sapiens)7247735RGDDNA:SNP:intron:rs2975760 (human) 
Capn10 ISOCAPN10 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:23349674
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