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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736560
Species: Homo sapiens
RGD Object: Gene
Symbol: EPHX1
Name: epoxide hydrolase 1
Acc ID: CHEBI:15882
Term: phenol
Definition: An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.
Chemical ID: MESH:D019800
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPHX1multiple interactionsISOEphx1 (Rattus norvegicus)6480464CTDEPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [CYP2E1 protein results in increased metabolism of Phenol]PMID:8211999
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