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GENE - TERM ANNOTATION REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: HP:0002659
Term: Increased susceptibility to fractures
Definition: An abnormally increased tendency to fractures of bones caused by an abnormal reduction in bone strength that is generally associated with an increased risk of fracture.
Definition Source(s): https://orcid.org/0009-0006-4530-3154
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1 IAGP 10045832RGDDNA:SNPs, haplotypes:introns: (rs9397448, rs2234693, rs1643821) 
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