Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	736559
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	ESR1
Name:	estrogen receptor 1

Acc ID:	CHEBI:47898
Term:	4'-epidoxorubicin
Definition:	An anthracycline that is the 4'-epi-isomer of doxorubicin.
Chemical ID:	MESH:D015251

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
ESR1	multiple interactions	EXP		6480464	CTD	Epirubicin binds to and results in decreased activity of ESR1 protein	PMID:25752796

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.