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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: CHEBI:4489
Term: Diallyl sulfide
Definition: An organic sulfide that has formula C6H10S.
Chemical ID: MESH:C038491
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1decreases expressionEXP 6480464CTDallyl sulfide results in decreased expression of ESR1 protein alternative formPMID:34724321
ESR1multiple interactionsEXP 6480464CTDESR1 protein alternative form promotes the reaction [allyl sulfide inhibits the reaction [Estradiol results in decreased cleavage of CASP3 protein]]; ESR1 protein alternative form promotes the reaction [allyl sulfide inhibits the reaction [Estradiol results in decreased expression of BAX protein]]; ESR1 protein alternative form promotes the reaction [allyl sulfide inhibits the reaction [Estradiol results in increased expression of BCL2 protein]]PMID:34724321
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