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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: CHEBI:35064
Term: alpha-Zearalanol
Definition: A macrolide that has formula C18H26O5.
Chemical ID: MESH:D015029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1affects bindingEXP 6480464CTDZeranol binds to ESR1 proteinPMID:19913605 PMID:30742918
ESR1increases activityEXP 6480464CTDZeranol results in increased activity of ESR1 proteinPMID:11331656
ESR1affects bindingISOEsr1 (Mus musculus)6480464CTDZeranol binds to ESR1 proteinPMID:19913605
ESR1affects bindingISOEsr1 (Rattus norvegicus)6480464CTDZeranol binds to ESR1 proteinPMID:19913605
ESR1multiple interactionsISOEsr1 (Rattus norvegicus)6480464CTD[Zeranol co-treated with butylbenzyl phthalate] affects the expression of ESR1 proteinPMID:35163327
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