GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ESR1 | affects response to substance | EXP | | 6480464 | CTD | ESR1 protein affects the susceptibility to Mercuric Chloride | PMID:12746304 | ESR1 | decreases expression | EXP | | 6480464 | CTD | Mercuric Chloride results in decreased expression of ESR1 mRNA; Mercuric Chloride results in decreased expression of ESR1 protein | PMID:12746304 | ESR1 | increases activity | EXP | | 6480464 | CTD | Mercuric Chloride results in increased activity of ESR1 protein | PMID:12746304 PMID:17716812 | ESR1 | multiple interactions | EXP | | 6480464 | CTD | Mercuric Chloride inhibits the reaction [Estradiol binds to ESR1 protein] | PMID:12746304 | |
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