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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736559
Species: Homo sapiens
RGD Object: Gene
Symbol: ESR1
Name: estrogen receptor 1
Acc ID: CHEBI:3093
Term: bifenthrin
Definition: A carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.
Chemical ID: MESH:C099952
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ESR1affects bindingEXP 6480464CTDbifenthrin binds to ESR1 proteinPMID:32278787
ESR1decreases expressionEXP 6480464CTDbifenthrin results in decreased expression of ESR1 mRNAPMID:20097460
ESR1multiple interactionsEXP 6480464CTDbifenthrin binds to and results in increased activity of ESR1 proteinPMID:33049310
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