GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | affects expression | EXP | | 6480464 | CTD | Sodium Fluoride affects the expression of SQSTM1 protein | PMID:30225638 | Sqstm1 | decreases expression | EXP | | 6480464 | CTD | Sodium Fluoride results in decreased expression of SQSTM1 mRNA; Sodium Fluoride results in decreased expression of SQSTM1 protein | PMID:29505816 PMID:30225638 PMID:34536393 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [Sodium Fluoride results in decreased expression of SQSTM1 protein]; TGFB1 protein promotes the reaction [Sodium Fluoride results in decreased expression of SQSTM1 mRNA]; TGFB1 protein promotes the reaction [Sodium Fluoride results in decreased expression of SQSTM1 protein] | PMID:29505816 PMID:34536393 | Sqstm1 | multiple interactions | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 mRNA; [[sodium arsenite results in increased abundance of Arsenic] co-treated with [Sodium Fluoride results in increased abundance of Fluorides]] results in increased expression of SQSTM1 protein; [Sodium Fluoride results in increased abundance of Fluorides] which results in increased expression of SQSTM1 mRNA; [Sodium Fluoride results in increased abundance of Fluorides] which results in increased expression of SQSTM1 protein | PMID:31844926 | | ||||||||||||||||||||||
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