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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735982
Species: Homo sapiens
RGD Object: Gene
Symbol: MITF
Name: melanocyte inducing transcription factor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MITFincreases expressionEXP 6480464CTDEstradiol results in increased expression of MITF mRNAPMID:19619570
MITFmultiple interactionsEXP 6480464CTD[Estradiol co-treated with EGF protein] results in increased expression of MITF mRNA; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MITF mRNAPMID:19619570 PMID:24758408
MITFincreases expressionISOMitf (Mus musculus)6480464CTDEstradiol results in increased expression of MITF mRNAPMID:19484750
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