Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735602
Species: Mus musculus
RGD Object: Gene
Symbol: Bmp2
Name: bone morphogenetic protein 2
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bmp2multiple interactionsISOBMP2 (Homo sapiens)6480464CTDMetformin inhibits the reaction [BMP2 protein results in decreased expression of CDH1 mRNA]; Metformin inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]; Metformin inhibits the reaction [BMP2 protein results in increased expression of BMP4 mRNA]; Metformin inhibits the reaction [BMP2 protein results in increased expression of RUNX2 mRNA]; Metformin inhibits the reaction [BMP2 protein results in increased expression of RUNX2 protein]; Metformin inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA]; Metformin inhibits the reaction [BMP2 protein results in increased expression of SP7 protein]; Metformin inhibits the reaction [BMP2 protein results in increased expression of VIM mRNA]PMID:37409753
Go Back to source page   Continue to Ontology report