GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NR1H4 | decreases expression | ISO | Nr1h4 (Rattus norvegicus) | 15045610 | RGD | cholesterol decreases expression of Nr1h4 mRNA in liver | | NR1H4 | multiple interactions | EXP | | 6480464 | CTD | [FGF19 protein results in increased phosphorylation of NR1H4 protein] which results in increased export of Cholesterol; Dasatinib inhibits the reaction [[FGF19 protein results in increased phosphorylation of NR1H4 protein] which results in increased export of Cholesterol]; NR1H4 protein mutant form inhibits the reaction [[FGF19 protein results in increased phosphorylation of NR1H4 protein] which results in increased export of Cholesterol]; SRC protein promotes the reaction [[FGF19 protein results in increased phosphorylation of NR1H4 protein] which results in increased export of Cholesterol] | PMID:30996006 | NR1H4 | increases export | ISO | Nr1h4 (Mus musculus) | 6480464 | CTD | NR1H4 protein results in increased export of Cholesterol | PMID:30996006 | | ||||||||||||||||||||||
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