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GENE - TERM ANNOTATION REPORT

RGD ID: 731859
Species: Mus musculus
RGD Object: Gene
Symbol: Nf2
Name: neurofibromin 2
Acc ID: DOID:9003566
Term: Mesothelioma
Definition: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Definition Source(s): MESH:D008654
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nf2 ISONF2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:12136076 PMID:12168054 PMID:12802287 PMID:16166281 PMID:16319530 PMID:18835652
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