GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ces1d | decreases metabolic processing | ISO | CES1 (Homo sapiens) | 6480464 | CTD | CES1 gene mutant form results in decreased metabolism of 4-nitrophenyl acetate | PMID:18485328 | Ces1d | increases hydrolysis | ISO | CES1 (Homo sapiens) | 6480464 | CTD | CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate | PMID:10518925 PMID:20097249 | Ces1d | increases metabolic processing | ISO | CES1 (Homo sapiens) | 6480464 | CTD | CES1 protein results in increased metabolism of 4-nitrophenyl acetate | PMID:18485328 | Ces1d | multiple interactions | ISO | CES1 (Homo sapiens) | 6480464 | CTD | [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] which results in increased chemical synthesis of 4-nitrophenol; Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; CES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl acetate; Fluoxetine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] | PMID:16282638 PMID:20097249 | |
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