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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jmjd1c
Name: jumonji domain containing 1C
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jmjd1cdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of JMJD1C mRNAPMID:25181051 PMID:32145629
Jmjd1cincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of JMJD1C genePMID:28505145
Jmjd1cdecreases methylationISOJMJD1C (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of JMJD1C genePMID:31601247
Jmjd1cmultiple interactionsISOJMJD1C (Homo sapiens)6480464CTD[bisphenol A binds to and affects the folding of AR protein] inhibits the reaction [AR protein modified form binds to JMJD1C protein modified form]PMID:28751236
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