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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708417
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt2b7
Name: UDP glucuronosyltransferase family 2 member B7
Acc ID: CHEBI:9144
Term: silibinin
Definition: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
Chemical ID: MESH:C440975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt2b7multiple interactionsISOUGT2B7 (Homo sapiens)6480464CTDSilybin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin]PMID:15155549
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