GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Thapsigargin results in increased phosphorylation of MAPK1 protein | PMID:21147958 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK1 protein]; Egtazic Acid inhibits the reaction [Thapsigargin results in increased activity of MAPK1 protein]; Thapsigargin results in increased activity of and results in increased phosphorylation of MAPK1 protein | PMID:11914123 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Thapsigargin results in increased phosphorylation of MAPK1 protein | PMID:15339911 PMID:20850495 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK1 protein]; [1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Genistein] inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]]; Genistein inhibits the reaction [Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]]; Thapsigargin promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] | PMID:15339911 PMID:16251475 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | [Thapsigargin co-treated with HRAS protein] results in decreased phosphorylation of MAPK1 protein; Thapsigargin inhibits the reaction [cypermethrin results in increased phosphorylation of and results in increased activity of MAPK1 protein] | PMID:24898257 PMID:29149324 | | ||||||||||||||||||||||
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