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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:73357
Term: U69593
Definition: A monocarboxylic acid amide obtained by formal condensation between the carboxy group of phenylacetic acid and the secodary amino group of (5R,7S,8S)-N-methyl-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-amine.
Chemical ID: MESH:C045444
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases phosphorylationISOMapk1 (Mus musculus)6480464CTDU 69593 results in increased phosphorylation of MAPK1 proteinPMID:16954126
Mapk1multiple interactionsISOMapk1 (Mus musculus)6480464CTDnorbinaltorphimine inhibits the reaction [U 69593 results in increased phosphorylation of MAPK1 protein]PMID:16954126
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