GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Temozolomide results in increased phosphorylation of MAPK1 protein | PMID:36176197 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | [Temozolomide results in decreased susceptibility to Temozolomide] inhibits the reaction [Temozolomide results in increased phosphorylation of MAPK1 protein]; [Temozolomide results in decreased susceptibility to Temozolomide] inhibits the reaction [thymoquinone results in increased phosphorylation of MAPK1 protein]; [Temozolomide results in decreased susceptibility to Temozolomide] inhibits the reaction [U 0126 results in decreased phosphorylation of MAPK1 protein]; [Temozolomide results in decreased susceptibility to Temozolomide] promotes the reaction [[thymoquinone co-treated with SB 203580] results in increased phosphorylation of MAPK1 protein]; [Temozolomide results in decreased susceptibility to Temozolomide] promotes the reaction [thymoquinone results in increased phosphorylation of MAPK1 protein] | PMID:36176197 | |
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