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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:6950
Term: mirtazapine
Definition: A tetracyclic antidepressant that has formula C17H19N3.
Chemical ID: MESH:C035133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1multiple interactionsISOSREBF1 (Homo sapiens)6480464CTDmirtazapine results in increased cleavage of and results in increased activity of SREBF1 proteinPMID:16324787
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