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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Acc ID: CHEBI:30537
Term: triphenylstannane
Definition: An organotin compound that has formula C18H16Sn.
Chemical ID: MESH:C030665
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11a1decreases expressionEXP 6480464CTDtriphenyltin results in decreased expression of CYP11A1 mRNA; triphenyltin results in decreased expression of CYP11A1 proteinPMID:31765896 PMID:35489455
Cyp11a1multiple interactionsEXP 6480464CTD[triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of CYP11A1 mRNA; [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of CYP11A1 proteinPMID:30772500
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