GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp11a1 | affects expression | ISO | CYP11A1 (Homo sapiens) | 6480464 | CTD | Hydrocortisone affects the expression of CYP11A1 mRNA | PMID:30528684 | Cyp11a1 | decreases expression | ISO | CYP11A1 (Homo sapiens) | 6480464 | CTD | Hydrocortisone results in decreased expression of CYP11A1 mRNA; Hydrocortisone results in decreased expression of CYP11A1 protein | PMID:30528684 PMID:34454011 | Cyp11a1 | multiple interactions | ISO | CYP11A1 (Homo sapiens) | 6480464 | CTD | HDAC1 protein affects the reaction [Hydrocortisone results in decreased expression of CYP11A1 mRNA]; Mifepristone inhibits the reaction [Hydrocortisone results in decreased expression of CYP11A1 mRNA] | PMID:34454011 | |
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