GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slco1b2 | affects response to substance | ISO | Slco1b2 (Mus musculus) | 6480464 | CTD | SLCO1B2 protein affects the susceptibility to Phalloidine | PMID:18296417 | Slco1b2 | increases expression | ISO | Slco1b2 (Mus musculus) | 6480464 | CTD | Phalloidine results in increased expression of SLCO1B2 mRNA | PMID:25280775 | Slco1b2 | increases uptake | ISO | SLCO1B3 (Homo sapiens) | 6480464 | CTD | SLCO1B3 protein results in increased uptake of Phalloidine | PMID:19464309 PMID:25280775 | Slco1b2 | increases uptake | ISO | Slco1b2 (Mus musculus) | 6480464 | CTD | SLCO1B2 protein results in increased uptake of Phalloidine | PMID:25280775 | Slco1b2 | multiple interactions | ISO | Slco1b2 (Mus musculus) | 6480464 | CTD | [KEAP1 gene mutant form results in decreased susceptibility to Phalloidine] which results in increased expression of SLCO1B2 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Phalloidine] which results in increased expression of SLCO1B2 mRNA; Oleanolic Acid inhibits the reaction [Phalloidine results in increased expression of SLCO1B2 mRNA] | PMID:25280775 | | ||||||||||||||||||||||
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