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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69032
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGES
Name: prostaglandin E synthase
Acc ID: CHEBI:48607
Term: lithium chloride
Definition: A metal chloride salt with a Li(+) counterion.
Chemical ID: MESH:D018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGESincreases expressionISOPtges (Mus musculus)6480464CTDLithium Chloride results in increased expression of PTGES proteinPMID:19692487
PTGESmultiple interactionsISOPtges (Mus musculus)6480464CTD[Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]; PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]PMID:19692487
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