GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aqp9 | increases expression | ISO | AQP9 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of AQP9; Tretinoin results in increased expression of AQP9 mRNA; Tretinoin results in increased expression of AQP9 protein | PMID:16968895 PMID:22940758 PMID:30093655 PMID:33167477 | Aqp9 | multiple interactions | ISO | AQP9 (Homo sapiens) | 6480464 | CTD | [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of AQP9 mRNA; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased import of Arsenic Trioxide; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased susceptibility to Arsenic Trioxide; AQP9 protein affects the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein]] | PMID:16968895 PMID:19225113 PMID:30093655 | | ||||||||||||||||||||||
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