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GENE - TERM ANNOTATION REPORT

RGD ID: 68407
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lrp2
Name: LDL receptor related protein 2
Acc ID: DOID:5394
Term: prolactinoma
Definition: A pituitary adenoma which secretes PROLACTIN, leading to HYPERPROLACTINEMIA. Clinical manifestations include AMENORRHEA; GALACTORRHEA; IMPOTENCE; HEADACHE; visual disturbances; and CEREBROSPINAL FLUID RHINORRHEA.
Definition Source(s): MESH:D015175
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lrp2 ISOLRP2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Prolactinoma, familialPMID:17632512 PMID:25682901 PMID:25741868 PMID:28492532
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