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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68339
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fads2
Name: fatty acid desaturase 2
Acc ID: CHEBI:17439
Term: cyanocob(III)alamin
Definition: A complex cob(III)alamin in which cobalt is positioned in the centre of a planar corrin tetrapyrrole ring and bound axially to a 5,6-dimethylbenzimidazole moiety and a cyano group. It is one of several forms of the vitamin known as vitamin B12.
Chemical ID: MESH:D014805
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fads2multiple interactionsEXP 6480464CTD[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS2 protein; [Vitamin B 12 deficiency co-treated with Folic Acid] results in decreased activity of FADS2 protein; Folic Acid inhibits the reaction [[Vitamin B 12 deficiency co-treated with Fatty Acids, Omega-3] results in decreased activity of FADS2 protein]PMID:22133376
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