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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67377
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd3b2
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Acc ID: CHEBI:34757
Term: fenitrothion
Definition: An organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4.
Chemical ID: MESH:D005278
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd3b2decreases expressionEXP 6480464CTDFenitrothion results in decreased expression of HSD3B2 mRNAPMID:26264430
Hsd3b2multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Fenitrothion results in decreased expression of HSD3B2 mRNA]PMID:26264430
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