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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631365
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nampt
Name: nicotinamide phosphoribosyltransferase
Acc ID: CHEBI:16797
Term: 1-methylnicotinamide
Definition: A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Chemical ID: MESH:C024058
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Namptmultiple interactionsEXP 6480464CTDN(1)-methylnicotinamide inhibits the reaction [Letrozole results in increased expression of NAMPT mRNA]PMID:32298659
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