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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9multiple interactionsEXP 6480464CTD[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]PMID:22085843
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTD[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein; Copper inhibits the reaction [IAPP protein results in increased phosphorylation of MAPK9 protein]PMID:23793354 PMID:24690739
Mapk9multiple interactionsISOMapk9 (Mus musculus)6480464CTD[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 proteinPMID:24690739
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