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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628846
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4a8
Name: cytochrome P450, family 4, subfamily a, polypeptide 8
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4a8affects expressionEXP 6480464CTDClofibrate affects the expression of CYP4A8 mRNAPMID:19483382
Cyp4a8decreases expressionEXP 6480464CTDClofibrate results in decreased expression of CYP4A8 mRNAPMID:18670166
Cyp4a8increases expressionEXP 6480464CTDClofibrate results in increased expression of CYP4A8 mRNAPMID:12851107
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