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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mfn2
Name: mitofusin 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mfn2increases expressionEXP 6480464CTDbisphenol A results in increased expression of MFN2 mRNAPMID:25181051
Mfn2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of MFN2 genePMID:28505145
Mfn2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of MFN2 mRNAPMID:36041667
Mfn2decreases expressionISOMfn2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of MFN2 mRNA; bisphenol A results in decreased expression of MFN2 proteinPMID:34186417 PMID:38021376
Mfn2increases expressionISOMFN2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of MFN2 proteinPMID:34186270
Mfn2increases expressionISOMfn2 (Mus musculus)6480464CTDbisphenol A results in increased expression of MFN2 mRNAPMID:33221593
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