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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mfn2
Name: mitofusin 2
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mfn2multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MFN2 protein]PMID:27997345 PMID:37499777
Mfn2multiple interactionsISOMFN2 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of MFN2 protein]PMID:37084995
Mfn2multiple interactionsISOMfn2 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein]PMID:31408635
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