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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628774
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l11
Name: Bcl2-like 11
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l11increases expressionEXP 6480464CTDMethamphetamine results in increased expression of BCL2L11 proteinPMID:34214594
Bcl2l11multiple interactionsEXP 6480464CTD4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein]PMID:34214594
Bcl2l11increases expressionISOBCL2L11 (Homo sapiens)6480464CTDMethamphetamine results in increased expression of BCL2L11 proteinPMID:23820845
Bcl2l11multiple interactionsISOBCL2L11 (Homo sapiens)6480464CTD[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 proteinPMID:23820845
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