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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628774
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l11
Name: Bcl2-like 11
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l11affects expressionEXP 6480464CTDbisphenol A affects the expression of BCL2L11 mRNAPMID:25181051
Bcl2l11increases methylationEXP 6480464CTDbisphenol A results in increased methylation of BCL2L11 genePMID:28505145
Bcl2l11affects expressionISOBCL2L11 (Homo sapiens)6480464CTDbisphenol A affects the expression of BCL2L11 mRNAPMID:21826169
Bcl2l11decreases expressionISOBCL2L11 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of BCL2L11 mRNAPMID:22576693
Bcl2l11increases expressionISOBcl2l11 (Mus musculus)6480464CTDbisphenol A results in increased expression of BCL2L11 mRNA; bisphenol A results in increased expression of BCL2L11 proteinPMID:24909818 PMID:32407858
Bcl2l11increases methylationISOBCL2L11 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of BCL2L11 genePMID:22576693
Bcl2l11increases methylationISOBcl2l11 (Mus musculus)6480464CTDbisphenol A results in increased methylation of BCL2L11 promoterPMID:27312807
Bcl2l11multiple interactionsISOBCL2L11 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L11 mRNAPMID:28628672
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