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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:35553
Term: perhexiline
Definition: A piperidine that has formula C19H35N.
Chemical ID: MESH:D010480
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3multiple interactionsISODDIT3 (Homo sapiens)6480464CTD[perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of DDIT3 mRNA; [perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of DDIT3 protein; CYP2D6 protein inhibits the reaction [[perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of DDIT3 mRNA]; CYP2D6 protein inhibits the reaction [[perhexiline maleate results in increased abundance of Perhexiline] which results in increased expression of DDIT3 protein]PMID:36083301
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