GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit3 | increases expression | EXP | | 6480464 | CTD | Acrolein results in increased expression of DDIT3 protein | PMID:34813903 | Ddit3 | multiple interactions | EXP | | 6480464 | CTD | [Acrolein promotes the reaction [DDIT3 protein binds to PPARG promoter]] which results in decreased expression of PPARG protein; Acrolein promotes the reaction [DDIT3 protein binds to PPARG promoter]; Resveratrol inhibits the reaction [Acrolein results in increased expression of DDIT3 protein] | PMID:34813903 | Ddit3 | increases expression | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | Acrolein results in increased expression of DDIT3 mRNA; Acrolein results in increased expression of DDIT3 protein | PMID:28119953 PMID:29414845 | Ddit3 | increases expression | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | Acrolein results in increased expression of DDIT3 mRNA | PMID:21703327 | Ddit3 | multiple interactions | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of DDIT3 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Acrolein results in increased expression of DDIT3 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]; oleuropein inhibits the reaction [Acrolein results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]] | PMID:29414845 | Ddit3 | multiple interactions | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | Acrolein results in increased expression of and affects the localization of DDIT3 protein | PMID:18951912 | | ||||||||||||||||||||||
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